At the LDS Church Missionary Training Center in Provo, Utah, a devout, handsome, supercilious missionary-to-be, Elder Kevin Price, leads his classmates in a demonstration of the door-to-door to attempt to convert people to Mormonism ("Hello!"). One of the missionaries, Elder Arnold Cunningham, is an insecure, overweight, incorrigible nerd who tries to join in, but is completely hopeless. Price believes if he prays enough, he will be sent to Orlando, Florida for his two-year mission, but he and Cunningham are sent to Uganda as a pair ("Two By Two"). After saying goodbye to their families, the elders board a plane at the Salt Lake City airport. Price is sure he's destined to do something incredible (on his own), while Cunningham is just happy to have a best friend – one he met just the previous day ("You And Me (But Mostly Me)").